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- Unintentional weight loss is common in people with COPD and nutritional management has an important role
- Weight loss is related to decreased exercise capacity, health status and increased morbidity
- Opportunities for dietary and nutritional interventions in COPD management should be explored, aiming at early detection
Weight loss is common in people with COPD
In people with chronic obstructive pulmonary disease (COPD), energy requirements have been reported to be 15–20%
above normal needs due to the increased energy required for breathing. People with COPD are generally underweight and
have reduced muscle mass.1 One United Kingdom based study showed that 23% of subjects with COPD were classified
as malnourished. The malnourished subjects had lower lung function measurements, had more dietary problems and had lower
nutritional intake compared with the adequately nourished subjects.2
Careful balancing of caloric intake is required. One study showed that a total caloric intake in excess of 50% above
need was associated with poorer outcomes, while caloric intake of 30% above need was beneficial.3
Referral to a dietitian is recommended to establish an appropriate diet for a person with COPD who is malnourished.
Eating small, frequent meals may help to reduce dyspnoea
As COPD progresses, many people find that breathing becomes more difficult if they eat a heavy meal, so in this situation,
eating frequent, small and nutritious (high energy, high protein) meals is best. If people with COPD are not managing
to keep their weight above a desired level they may require dietary assistance.4
Evidence for nutritional support is limited
Evidence supporting the use of nutritional supplements for people with COPD is limited. A 2005 Cochrane review found
no evidence that nutritional supplementation makes a significant difference to weight gain or health outcomes in people
Despite this lack of evidence, international guidelines for the management of COPD in adults suggest that nutritional
supplements may improve nutritional status for patients with COPD who are malnourished. Patients using oral nutritional
supplements should also be encouraged to exercise regularly to build muscle mass.6
The American Thoracic Society also recommends considering nutritional supplementation for people who have involuntary
weight loss of more than 10% in the last six months or more than 5% in the past month.7
Nutritional management of patients with severe COPD is challenging and interventions should be extended to the early
detection and further prevention of weight loss before patients become malnourished.
A late manifestation of COPD is hypercapnia. It is caused by a reduction in ventilatory drive and is a feature of severe
In theory, under ideal conditions, dietary fat utilisation produces less CO2 per O2 molecule consumed
than carbohydrate. However, most studies indicate that consuming excess calories is a more important contributor to increased
CO2 production than the fat composition of the food.3
Higher fat supplements have been found to delay gastric emptying. This may be important in determining patient tolerance
of these formulas as a delay in gastric emptying can lead to extended periods of abdominal distention.
Pulmocare is a high fat, low carbohydrate formula designed to minimise CO2 retention in
chronic or acute respiratory insufficiency.
Subsidy for Pulmocare (which contains 1.5 Kcal/mL in 237 mL cans) is available under Special Authority
from a specialist or vocationally registered GP for patients who have COPD and have hypercapnia and need the supplement
as part of, or as a complete, diet.
GPs role in the nutritional care of people with COPD
Encourage patients with COPD to make and maintain dietary changes to minimise involuntary weight loss and nutritional
For those who have lost weight encourage Food First strategies (see Nutrition Support
Advise people with COPD who become breathless when eating, to eat frequent small meals.
Consider oral nutritional supplements for patients who have been identified at risk of malnutrition (BMI < 18.5kg/m2 or
unintentional weight loss > 10% within the last three to six months or a BMI < 20kg/m2 and unintentional
weight loss > 5% within the last three to six months).
For patients who develop hypercapnia, a specialist respiratory oral nutritional supplement may be of value.
Consider referral for dietetic assessment if BMI remains low.6
Thank you to Dr Lisa Houghton, Lecturer, Department of Human Nutrition, University of Otago, for expert
guidance in developing the original article which appeared in BPJ 15 (Aug,
- Hugli O, Schutz Y, Fitting JW. The daily energy expenditure in stable chronic obstructive pulmonary disease. Am J
Respir Crit Care Med 1996; 153:294–300.
- Cochrane W, Afolabi O. Investigation into the nutritional status, dietary intake and smoking habits of patients with
chronic obstructive pulmonary disease. J Hum Nutr Diet. 2004 Feb;17(1):3-11.
- Mallampalli A. Nutritional management of the patient with chronic obstructive pulmonary disease. Nutr Clin Prac 2004;19(6):550-6.
- Thoracic Society of Australia and New Zealand and Australian Lung Foundation. The COPDX plan: Australian and New
Zealand guidelines for the management of chronic obstructive pulmonary disease. April 2006. Available from:
- Ferreira IM, Brooks D, Lacasse Y, et al. Nutritional supplementation for stable chronic obstructive pulmonary disease.
Cochrane Database Syst Rev 2005;2:CD000998.
- National Institute for Health and Clinical Excellence (NICE). Management of chronic obstructive pulmonary disease
in adults in primary and secondary care (partial update). NICE, 2010. Available from:
- American Thoracic Society/European Respiratory Society Statement on Pulmonary Rehabilitation. Am J Respir Crit Care